For that reason, you should be careful taking pine bark if you have hypertension or diabetes. (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Used early on, it may prevent eye damage and blindness from diabetes [34]. blood in the urine. DIM and other plant indoles are found in . 1. According to a study of 170 women, low-dose pycnogenol (60 mg/day) may improve menopausal symptoms over 3 months, including night sweats, hot flashes, insomnia and sleep problems [69]. So it . (2004). The specific tree from which the bark is extracted is called a maritime pine. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. This supplement possibly activates the immune system. What gives pine bark extract its notoriety as a powerful ingredient and super antioxidant is that its loaded with oligomeric proanthocyanidin compounds, OPCs for short. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. Possess Anti-Inflammatory Action. Remember to speak with a doctor before taking Pycnogenol. According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Can Pycnogenol help? Note that each number in parentheses [1, 2, 3, etc.] For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. (2013). Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. The Benefits of DIM. There's good evidence that pycnogenol helps with eye damage caused by diabetes. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. Enzogenol also may reduce mental fatigue and sleep problems [82]. Are there any risks to taking it? Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. As a skin powder, however, you can use it safely for up to six weeks. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. Regardless, a natural option is available and far worth the wait. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Pycnogenol also potentially improved cognitive function in 78 people with mild cognitive impairment. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. The combination of Panax ginseng and vitamin E also appears to have an effect. Helps Treat Erectile Dysfunction. More research is needed to see how this supplement affects all of these conditions. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. Speak with your doctor before supplementing. One study involved a four-week treatment period followed by one week of no treatment or observation period. It also seems to help with cell regeneration and replication. Possible side effects . The . She loves communicating science and empowering people to achieve their optimal health. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. Can you get pycnogenol naturally from foods? A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. Both supplements are antioxidants, which have been shown to help with blood flow and erectile function. 1 Anti-Aging Beverage, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, What Is a Marionberry? That said, there are some instances where this extract may possibly be effective. A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Here are 12 benefits of ginkgo biloba. Disease of the retina in the eye. Pycnogenol; Pycnogenol. (11, 12), While both eliminate pain, the pine bark extract is a far better choice. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. Prunes and prune juice have many health benefits. During the first month on L-arginine, only five percent of patients experienced normal erection. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. It also reduced the size of scars. The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Read More: Health Benefits of Peanut Butter. which enables users to obtain detailed information and reports based on their genome. 1) Encourages Healthy Blood Pressure. Studies have also safely used Pycnogenol in children and during pregnancy. Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. Learn more about how to get even skin tone. Erythritol: Is This Healthy Sweetener the Real Deal? In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. Start with a low dose so you can be sure it doesnt cause any side effects. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. New research shows . Pycnogenol may help with other conditions as well. Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . Pycnogenol may stimulate the immune system. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. Headaches. As noted, aspirin can cause severe gastrointestinal issues. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. 1. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. However, its always a good idea to start with a low dose so you can monitor how your body responds. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Chestnut seed extract did not do as well. Abdominal pain was by far the most . (2017). This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Take Helpful Supplements. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . whole-body health. You should also avoid using pine bark extract without talking to your doctor first if you: You should also do additional research or talk to your doctor before taking pine bark extract if you also take: While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. For asthma in children: 1 milligram per pound of body weight given in two divided doses. DOI: Chowdhury WK, et al. For mild high blood pressure: 200 milligrams daily. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. 5) Vein Diseases and Swelling. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Pycnogenol significantly improved the heavy feeling as well as the swelling. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. Rare cases of liver disease. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. Dr. Eric L. Zielinski is a sought-after natural . In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. Add to Cart. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. Proper nutrition is essential for ADHD treatment. Sort By. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. But the actual bioavailability of this complex mixture is still unknown. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. 7. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. Potential for allergy when taken orally or used on the skin. Discover what the research says about elimination diets, foods to eat, and more. Pine bark extract is composed of 80% to 85% proanthocyanidins, the monomers catechin and taxifolin (5%), and phenolic acids, including derivatives of benzoic and cinnamic acids (2% to 4%). Theres evidence that Pycnogenol may be a promising nootropic for various groups of people, including middle-aged professionals, students, and people with mild cognitive decline like brain fog. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. 5. All rights reserved. Purity and potency of Pycnogenolare continuously monitored . The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. While these results are promising, there isnt enough research to fully understand the effect of antioxidant levels on ADHD symptoms. Our website services, content, and products are for informational purposes only. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. For most people, pine bark extract doesnt cause any side effects. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. There havent been any studies looking at long-term liver damage. Some people who have asthma have higher levels of leukotrienes in their blood. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. $31.99. Some small studies suggest it may also protect against coronary artery disease and blood clots. Align your health hacks with your genes for optimal health & cognitive function. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. Eye health. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. . Pycnogenol can help control blood pressure, which helps improve overall heart health. Information is shared for educational purposes only. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. Pycnogenol in metabolic syndrome and related disorders [Abstract]. A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Add to Cart. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. During week, five without, treatment, reduction of cramps was maintained in all three groups. Diarrhea. They include: We need more research to know for sure if pycnogenol helps treat these conditions. They were treated with 200 mg of Pycnogenol daily or with placebo. Tell your doctor about any supplements you're taking, even if they're natural. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. Required fields are marked *. 10 Day Erection Delay Sex Pills. When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [26]. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. - Apply a hot compress to the anus or soaking it in a shallow tub of hot water several times a day. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. Pine bark extract comes from the inner bark of the Pinus pinaster tree, most commonly found in Europe. They were given Pycnogenolfor a period of 10 days. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Systolic blood pressure measures how much blood is pumping from your heart to your arteries. 3. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. For most people, pine bark extract doesn't cause any side effects. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. It has been studied for its effects on everything from mental function to treating high blood pressure. (4). Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. WebMD does not provide medical advice, diagnosis or treatment. Pycnogenol is a compound of natural chemicals. Pycnogenol accelerates wound healing and reduces scar formation [Abstract]. In a good-quality study, 100 patients with osteoarthritis of the knee were treated for three months either with 150 mg of Pycnogenol a day or placebo. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. Additionally, athletes have endured less cramping and muscle pain when using the extract. Regardless of what youre using it for, its best to start with the lowest possible dose. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. This is thought to be due to pine bark extracts ability to reduce oxidative stress and inflammation. In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. Organika Pycnogenol 50mg 50 Tablets . But what are its health benefits? Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol French maritime pine bark extract's 4 basic properties. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. It seems to lower blood pressure and improve blood flow to the legs. The extract has been widely studied for the past 40 . Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. is a clickable link to peer-reviewed scientific studies. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. Pycnogenol and Pine Bark Extract Supplements. 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin. Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Learn about this tree-based pill and how it might be able to help you. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. It may cause side effects such as: Risks. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. Today's Dietitian: "Pycnogenol Supplement Offers Promise for Managing a Variety of Conditions." 2. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. In a small/preliminary study of kids with asthma, pycnogenol helped improve symptoms. (2015). Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. Pycnogenol health benefits. Pycnogenol: A miracle component in reducing ageing and skin disorders. ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. Eliminate blood clots. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. returned. It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [1]. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials.

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